Never say die

This is a good summary of David Sinclair’s work (purchased by GlaxoSmithKline) in Forbes Magazine.

“Glaxo has concocted sirtuin boosters far more potent than resveratrol. Among other effects, the compounds lower blood sugar, and Glaxo is testing them to treat diabetes. But preliminary lab experiments suggest that sirtuins could have a role in everything from Alzheimer’s disease to colon cancer. “We are talking about retarding the progression of certain age-related diseases,” says Glaxo drug discovery head Patrick Vallance. “The application could be pretty broad.”